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Chemistry, cannabinoid profiles and what the evidence can actually support.
Science & CannabinoidsWeed breathalyzers exist, and some are sold to employers. None measures how high you are, and a federal lab found one reading often could not tell before from after. Why THC is so hard to breath-test, what the studies found, and where the law stands.
Science & CannabinoidsIn the lab and in mice, THC turns immune cells down. In people, the clearest measured effect is in smokers' lungs, and for the rest of the body the National Academies found too little evidence to say. Here is each layer, with its limits.
Science & CannabinoidsMany top search results say weed speeds up your gut. Three placebo-controlled human trials found THC slowed the stomach or relaxed the colon, and none sped it up. Here is what was measured, what the famous survey can't show, and what likely explains the urge.
Science & CannabinoidsTrichomes are the tiny glands where cannabis makes and stores its cannabinoids and terpenes. Here is the cell biology behind them, what clear, cloudy and amber heads actually tell you, why frostier is not the same as stronger, and what kief is.
Science & CannabinoidsCouch lock is real, but most explanations for it are not. Human studies tie heavy sedation after THC to dose and route, while the indica, CB2 and myrcene stories trace back to fuzzy labels, a receptor mix-up and mice given injections.
Science & CannabinoidsWeed is not officially a depressant, a stimulant or a hallucinogen: the US police drug recognition system gives cannabis its own category. Here is the evidence for each effect, and why the label matters when you mix it with real depressants.
Science & CannabinoidsNo study has shown that weed kills brain cells in people. The idea came from monkey and rat experiments. The better question is which effects fade in hours or weeks and which may last years, and the answer depends on age, how heavy the use is and what else was used.
Science & CannabinoidsMost pages blame terpenes. The skunk note in cannabis is a trace sulfur compound, a chemical cousin of skunk spray and the same molecule that skunks a beer. Here is what the chemistry shows, why the smell fades, and why it tells you nothing about potency.
Science & CannabinoidsMost pages say THC floods your brain with dopamine. Human brain scans found a real but small signal, and two studies found no significant change. Here is what dopamine really does, why the same high can turn to paranoia, and why CBD doesn't do it.
Science & CannabinoidsCBG and THCV get sold as the same daytime cannabinoid. They are different chemical families: THCV is THC with a shorter tail and does not even come from CBG. Here is what each has been measured for, what federal rules name, and what our certificates print.
Science & CannabinoidsCottonmouth comes from THC, not smoke: it shows up with swallowed THC and in placebo-controlled saliva studies. See how common it is, whether weed dehydrates you (modern human studies have not measured it), and why your teeth are the real concern.
Science & CannabinoidsResearchers have produced weed paranoia on purpose: 121 adults, 1.5 mg of intravenous THC, placebo-controlled. Here is what those trials found about what causes it, who it happens to, how much it takes, and whether CBD blocks it.
Science & CannabinoidsCannabis flavonoids are the plant's third family of compounds, and the best known, cannflavin, carries a famous number from a 1985 cell-culture test. Here is what that test measured, how little cannflavin the plant makes, and why a potency COA cannot confirm a flavonoid claim.
Science & CannabinoidsRed eyes after cannabis come from THC in the blood, not smoke: lab studies recorded them after injected, smoked and swallowed THC. See what was measured, why the blood pressure story fails for single doses, how long redness lasts, and what is still unknown.
Science & CannabinoidsPage one calls CBC and CBN two cannabinoids from the same plant. One has a purified enzyme behind it; the other has no enzyme at all. Here is the chemistry both ways, the counts on one dated day, and what both rows read on our 13 certificates.
Science & CannabinoidsPage one gives each of these three a job title and cites nothing. Here is what is checkable instead: the subtraction three certificates print, the cost per milligram both ways, and three evidence bases counted on the same day.
Science & CannabinoidsSearch results present CBC and CBG as two peers on a menu. In the plant they are one enzymatic step apart, and the step runs one way. Here is the branch, the July 2026 crystal structures, and what each row reads on our twelve batch certificates.
Science & CannabinoidsPHC is a label, not a settled molecule. On one search page, four sellers gave four incompatible chemistries for the same three letters, and the name does not resolve in PubMed, PubChem, MeSH, ClinicalTrials.gov, DEA's list or the patent literature.
Science & CannabinoidsIn 2016 an experiment turned CBD into THC in simulated gastric fluid, and every page that quotes it leaves out what was in the beaker: a detergent your stomach does not contain. Here are the actual yields, the human studies at 300, 700 and 4,500 mg, and the route that is real.
Science & CannabinoidsThree pages on the first page of results give three different potency multipliers for 11-hydroxy-THC. The measured story is simpler: it is what CYP2C9 makes from delta-9-THC, and the route you take THC by decides how much of the blood mixture it becomes.